Physician’s Profile

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Top Doctor: 
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Tony J. Wang, MD

Department of Radiation Oncology
Co-Director, Center for Radiosurgery
Introduction:

Tony J. C. Wang, M.D., is the Co-Director of the Center for Radiosurgery and an Associate Professor of Radiation Oncology (in Neurological Surgery) at New York Presbyterian/Columbia University Irving Medical Center. He is recognized nationally for his extensive expertise in malignant and benign brain tumors. His research interests are in Gamma Knife stereotactic radiosurgery and brain tumors resulting in over 50 peer-reviewed publications. He has given over 50 invited lectures and visiting professorships nationally and internationally.

He serves on several national and international working groups developing guidelines for brain tumor management and stereotactic radiosurgery. He is an editor for 2 radiation oncology textbooks and a writer for over 15 book chapters. He serves as an Associate Editor on the Radiation Oncology Section of Neurosurgery, the official journal of the Congress of Neurological Surgeons, and as a reviewer for International Journal of Radiation Oncology, Biology, and Physics, Practical Radiation Oncology, and Journal of Neuro-Oncology as well as many others.

Dr. Wang received his B.A. and M.D. degrees from University of Missouri Kansas City Medical School, during which time he was also a Clinical Research Training Program Fellow at the National Institutes of Health, Bethesda, Maryland. He received internship training at Flushing Hospital Medical Center. Dr. Wang received his radiation oncology training at New York Presbyterian Hospital (Columbia campus), where he was Chief Resident from 2011-2012.

As a member of the Brain Tumor Center and Pituitary Tumor Center at Columbia, Dr. Wang is part of a multidisciplinary team that brings expertise from multiple specialties, including neurosurgery, neuro-oncology, neuroradiology, and neuro-endocrinology.

Board Certificates
Radiation Oncology
Areas of Expertise:
  • Gamma Knife Radiosurgery
  • Brain & Spinal Tumors
  • Acoustic Neuroma
  • Anaplastic Astrocytoma
  • Brain Cancer
  • Brain Metastases
  • Brain Stem Glioma
  • Brain Tumor
  • Central Nervous System Tumors
  • Glioblastoma Multiforme
  • Gliomas
  • Graves' Disease
  • Image Guided Radiation Therapy
  • Meningioma
  • Orbital Tumor
  • Pituitary Neoplasm
  • Radiation Oncology
  • Radiosurgery
  • Spinal Tumors
  • Stereotactic Radiosurgery
  • Trigeminal Neuralgia
Publications:

Kinslow CJ, Garton ALA, Rae AI, Marcus LP, Adams CM, McKhann GM, Sisti MB, Connolly ES, Bruce JN, Neugut AI, Sonabend AM, Canoll P, Cheng SK, Wang TJC. Extent of resection and survival for oligodendroglioma: a u.s. population-based study. Journal of Neuro-Oncology. 2019.


Vulpe H, Save AV, Xu Y, Garrett MD, Wu CC, Cheng SK, Jani AH, Bruce JN, McKhann GM, Wang TJC, Sisti MB. Frameless Stereotactic Radiosurgery on the Gamma Knife Icon: Early Experience From 100 Patients. Neurosurgery. 2019.


Lassman AB, Aldape KD, Ansell PJ, Bain E, Curran WJ, Eoli M, French PJ, Kinoshita M, Looman J, Mehta M, Muragaki Y, Narita Y, Ocampo C, Roberts-Rapp L, Song M, Vogelbaum MA, Walenkamp AME, Wang TJC, Zhang P, van den Bent MJ. Epidermal growth factor receptor (egfr) amplification rates observed in screening patients for randomized trials in glioblastoma. Journal of Neuro-Oncology. 2019; 144:205-210.


Smith DR, Saadatmand HJ, Wu CC, Black PK, Wuu YR, Lesser J, Horan M, Isaacson SR, Wang TJC, Sisti MB. Treatment Outcomes and Dose Rate Effects Following Gamma Knife Stereotactic Radiosurgery for Vestibular Schwannomas. Neurosurgery. 2019.


Sperduto PW, Fang P, Li J, Breen W, Brown PD, Cagney D, Aizer A, Yu JB, Chiang V, Jain S, Gaspar LE, Myrehaug S, Sahgal A, Braunstein S, Sneed P, Cameron B, Attia A, Molitoris J, Wu CC, Wang TJC, Lockney NA, Beal K, Parkhurst J, Buatti JM, Shanley R, Lou E, Tandberg DD, Kirkpatrick JP, Shi D, Shih HA, Chuong M, Saito H, Aoyama H, Masucci L, Roberge D, Mehta MP. Estimating survival in patients with gastrointestinal cancers and brain metastases: an update of the graded prognostic assessment for gastrointestinal cancers (gi-gpa). Clinical and Translational Radiation Oncology. 2019; 18:39-45.


Vulpe H, Wang TJC. Commentary: gamma knife radiosurgery for multiple sclerosis-associated trigeminal neuralgia. Neurosurgery. 2019.


Yanagihara TK, Wang TJC. Commentary: treatment of asymptomatic meningioma with gamma knife radiosurgery: long-term follow-up with volumetric assessment and clinical outcome. Neurosurgery. 2019.


Wang TJC. Hypofractionated radiation therapy or staged stereotactic radiosurgery for large brain metastasis. International Journal of Radiation Oncology, Biology, and Physics. 2019; 104:484-485.


Boyett D, Kinslow CJ, Bruce SS, Sonabend AM, Rae AI, McKhann GM, Sisti MB, Bruce JN, Cheng SK, Wang TJC. Spinal location is prognostic of survival for solitary-fibrous tumor/hemangiopericytoma of the central nervous system. Journal of Neuro-Oncology. 2019; 143:457-464.


Chaudhary KR, Yan SX, Heilbroner SP, Sonett JR, Stoopler MB, Shu C, Halmos B, Wang TJC, Hei TK, Cheng SK. Effects of β–adrenergic antagonists on chemoradiation therapy for locally advanced non-small cell lung cancer. Journal of Clinical Medicine. 2019; 8:E575.


Kruser TJ, Bosch WR, Badiyan SN, Bovi JA, Ghia AJ, Kim MM, Solanki AA, Sachdev S, Tsien C, Wang TJC, Mehta MP, McMullen KP. NRG brain tumor specialists consensus guidelines for glioblastoma contouring. Journal of Neuro-Oncology. 2019; 143:157-166.


Smith DR, Bian Y, Wu CC, Saraf A, Tai CH, Nanda T, Yaeh A, Lapa ME, Andrews JIS, Cheng SK, McKhann GM, Sisti MB, Bruce JN, Wang TJC. Natural history, clinical course and predictors of interval time from initial diagnosis to development of subsequent NSCLC brain metastases. Journal of Neuro-Oncology. 2019; 143:145-155.


Sperduto PW, Fang P, Li J, Breen W, Brown PD, Cagney D, Aizer A, Yu J, Chiang V, Jain S, Gaspar LE, Myrehaug S, Sahgal A, Braunstein S, Sneed P, Cameron B, Attia A, Molitoris J, Wu CC, Wang TJC, Lockney N, Beal K, Parkhurst J, Buatti JM, Shanley R, Lou E, Tandberg DD, Kirkpatrick JP, Shi D, Shih HA, Chuong M, Saito H, Aoyama H, Masucci L, Roberge D, Mehta MP. Survival and Prognostic Factors in patients with gastrointestinal cancers and brain metastases: have we made progress? Translational Research. 2019; 208:63-72.


Wang TJC. Book Review: Adult cns radiation oncology: principles and practice. Neurosurgery. 2019.


Ivanov VN, Wu J, Wang TJC, Hei TK. Inhibitoin of atm kinase upregulates levels of cell death induced by cannabidiol and γ-irradiation in human glioblastoma cells. Oncotarget. 2019; 10:825-846.


Yanagihara TK, McFaline-Figueroa JR, Giacalone NJ, Lee AW, Soni V, Hwang ME, Hsieh KT, Saraf A, Wu CC, Yang D, Wen PY, Ashamalla H, Aizer AA, Wang TJC, Huang RY. A low percentage of metastases in deep brain and temporal lobe structures. Neuro-Oncology. 2019; 6:640-647.


Buss EJ, Wang TJC. Treatment of lung adenocarcinoma brain metastases: what is the role of radiotherapy in the age of precision medicine? Translational Lung Cancer Research. 2018; 7:S318-320.


Wang TJC, Mehta MP. Low-grade glioma radiotherapy treatment and trials. Neurosurgery Clinics of North America. 2019; 30:111-118.


Yanagihara TK, Wang TJC. Commentary: long-term hearing outcomes following stereotactic radiosurgery in vestibular schwannoma patients – a retrospective cohort study. Neurosurgery. 2018.


Schulte JD, Hargus G, Canoll P, Sisti MB, Wang TJC, Lignelli A, Lassman AB. Clinical reasoning: transient speech deficits in a patient with history of medulloblastoma. Neurology. 2018; 12:e1196-e1201.


Black PJ, Smith DR, Chaudhary K, Xanthopoulos EP, Chin C, Spina CS, Hwang ME, Mayeda M, Wang YF, Connolly EP, Wang TJC, Wuu CS, Hei TK, Cheng SK, Wu CC. Velocity-based adaptive registration and fusion for fractionated stereotactic radiosurgery using the small animal radiation research platform. International Journal of Radiation Oncology, Biology and Physics. 2018; 102:841-847.


Okunieff P, Casey-Sawicki K, Lockney NA, Hoppe BS, Enderling H, Pinnix CC, Welsh JW, Krishnan S, Yothers G, Brown JM, Knox SJ, Bristow RG, Spellman PT, Mitin T, Nabavizadeh N, Jaboin J, Manning HC, Feng FY, Galbraith SM, Solanki AA, Harkenrider MM, Tuli R, Decker RH, Finkelstein SE, Hsu CC, Ha CS, Jagsi R, Shumway D, Daly M, Wang TJC, Fitzgerald TJ, Laurie F, Marshall DT, Raben D, Constine LS, Thomas CR, Kachnic LA. Report from the swog radiation oncology committee: research objectives workshop 2017. Clinical Cancer Research. 2018; 24:3500-3509.


Rae AI, Mehta A, Cloney M, Kinslow CJ, Wang TJC, Bhagat G, Canoll PD, Zanazzi GJ, Sisti MB, Sheth SA, Connolly ES, McKhann GM, Bruce JN, Iwamoto FM, Sonabend AM. Craniotomy and survival for primary central nervous system lymphoma. Neurosurgery. 2019; 84:935-944.


Kinslow CJ, Bruce SS, Rae AI, Sheth SA, McKhann GM, Sisti B, Bruce JN, Sonabend AM, Wang TJC. Solitary-fibrous tumor/hemangiopericytoma of the central nervous system: a population-based study. Journal of Neuro-Oncology. 2018; 138:173-182.


Tai CH, Wu CC, Hwang ME, Saraf A, Grubb C, Jani A, Lapa ME, Andrews JIS, Isaacson SR, Sonabend AM, Sheth SA, McKhann GM, Sisti MB, Bruce JN, Cheng SK, Connolly EP, Wang TJC. Single institution validation of a modified graded prognostic assessment of patients with breast cancer brain metastases. CNS Oncology. 2018; 7:25-34.


Wang TJC, Brown PD. Brain metastases: fractionated whole-brain radiotherapy. Handbook of Clinical Neurology. 2018; 149:123-127.


Smith DR, Wu CC, Saadatmand HJ, Isaacson SR, Cheng SK, Sisti MB, Bruce, JN, Sheth SA, Lassman AB, Iwamoto FM, Wang SH, Canoll P, McKhann GM Nd, Wang TJC. Clinical and molecular characteristics of gliosarcoma and modern prognostic significance relative to conventional glioblastoma. Journal of Neuro-Oncology. 2018; 137:303-311


Nanda T, Yeah A, Wu CC, Jani A, Saad S, Qureshi YH, Cauley KA, Lesser J, Cheng SK, Isaacson SR, Sisti MB, Bruce JN, McKhann GM, Sheth SA, Lassman AB, Wang TJ. Local control and overall survival for adjuvant stereotactic radiosurgery in patients with residual or recurrent disease. Journal of Neuro-Oncology. 2018; 136:281-287.


Nanda T, Wu CC, Campbell AA, Bathras RM, Jani A, Kazim M, Wang TJ. Risk of dry eye syndrome in patient striated with whole-brain radiotherapy. Medical Dosimetry. 2017; 42:357-362.


Garrett MD, Yanagihara TK, Yeh R, McKhann GM, Sisti MB, Bruce JN, Sheth SA, Sonabend AM, Wang TJ. Monitoring radiation treatment effects in glioblastoma: flair volume as significant predictor of survival. Tomography. 2017; 3:131-137.


Wu CC, Chaudhry KR, Na YH, Welch D, Black PJ, Sonabend AM, Canoll P, Sanger YM, Wang TJC, Wuu CS, Hei TK, Cheng SK. Quality assessment of stereotactic radiosurgery of a melanoma brain metastases model using a mouse-like phantom and the small animal radiation research platform. International Journal of Radiation Oncology, Biology and Physics. 2017; 99:191-201.


Smith DR, Wu CC, Wang TJC. Stereotactic radiosurgery for treatment of multiple brian metastases: remembering to spare the hippocampus? In regard to Zhang et al. Practical Radiation Oncology. 2017; 7:446-447.


Saraf A, Grubb CS, Hwang ME, Tai CH, Wu CC, Jani A, Lapa ME, Andrews, JIS, Vanderkelen S, Isaacson SR, Sonabend AM, Sheth SA, McKhann GM, Sisti MB, Bruce JN, Cheng SK, Connolly EP, Wang TJC. Breast cancer subtype and stage are prognostic of time from breast cancer diagnosis to brain metastasis development. Journal of Neuro-Oncology. 2017; 134:453-463.


Wu CC, Smith DR, Chin C, Wang TJ. The success of nrg-gbm-rpa: biomarker-based classification, where to next? Translational Cancer Research. 2017; 6:S541-543.


Perni S, Wang TJ, Lesser J, Mandigo C, Isaacson SR, Horowitz DP. Gamma knife treatment of recurrent CNS metastases of pancreatic origin: a case report and review of the literature. CNS Oncology. 2017; 6:111-118.


Wu CC, Wuu YR, Jani A, Saraf A, Tai CH, Lapa ME, Andrew JIS, Tiwari A, Saadatmand HJ, Isaacson SR, Cheng SK, Wang TJC. Whole-brain irradiation field design: a comparison of parotid dose. Medical Dosimetry. 2017; 42:145-149.


Kinslow CJ, Rajpara RS, Wu CC, Bruce SS, Canoll PD, Wang SH, Sonabend AM, Sheth AM, McKhann GM, Sisti MB, Bruce JN,