Peter A Sims, PhD

  • Associate Professor of Systems Biology (in Biochemistry and Molecular Biophysics and in Systems Biology)
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Overview

Peter Sims, PhD is an Associate Professor in the Department of Systems Biology and Department of Biochemistry & Molecular Biophysics, Vagelos College of Physicians & Surgeons (VP&S). He is also the Faculty Director of the Columbia Single Cell Analysis Core, Scientific Director of the Sulzberger Columbia Genome Center, and co leads the Precision Oncology and Systems Biology program within the Herbert Irving Comprehensive Cancer Center (HICCC). His lab develops experimental and computational tools for genomic analysis with applications in cancer biology, immunology and neuroscience. Dr. Sims received his PhD in chemistry from Harvard University where he also conducted his postdoctoral research.

Academic Appointments

  • Associate Professor of Systems Biology (in Biochemistry and Molecular Biophysics and in Systems Biology)

Administrative Titles

  • Director, Columbia Single Cell Analysis Core
  • Co-Leader, Precision Oncology and Systems Biology Program, HICCC
  • Scientific Director, Sulzberger Columbia Genome Center, VP&S

Credentials & Experience

Education & Training

  • Postdoctoral Fellowship, Harvard University
  • BS, Chemistry, University of California San Diego
  • PhD, 2009 Chemistry, Harvard University

Committees, Societies, Councils

  • Member, Planning Committee, Chan Zuckerberg Biohub New York, 2023-present
  • Editorial Board, Genome Medicine, 2022-present
  • Guest Editor, Current Opinion in Systems Biology, Genetics and Epigenomics, 2018

Honors & Awards

Research Initiatives for Science and Engineering (RISE) Award, Columbia University, 2021
Emerging Leader Award, The Mark Foundation for Cancer Research, 2018
Research Initiatives for Science and Engineering (RISE) Award, Columbia University, 2014
Cold Spring Harbor Asia Fellowship, 2011
Biophysical Society Student Travel Award, 2008
American Chemical Society Contributed Talk Award, 2007
Delegate to the Annual Meeting of Nobel Laureates in Lindau, U.S. Dept. of Energy, 2006
Certificate of Distinction in Teaching, Harvard University, 2005, 2006
National Science Foundation Graduate Research Fellowship, 2004-2007
Joseph E. Mayer Award for Undergraduate Research, UCSD, 2004
Teaching Assistant Excellence Award, UCSD, 2004
Phi Beta Kappa, UCSD, 2003
Barry M. Goldwater Scholarship, 2003-2004

Research

The Sims Lab at Columbia University Medical Center focuses on the development of new technology for the application of systems biology in biomedicine. We recently developed and applied new experimental and computational methods for cell type-specific, genome-wide analysis of transcription and translation in complex tissues such as the brain. In addition, we have developed new technology for large-scale expression analysis of individual cells by combining cutting-edge microscopy, next-generation sequencing, and microfabrication. We apply these tools in several human disease contexts including brain tumors and other neurological disorders.

Research Interests: single-cell genomics, genomic technology development, computational biology, malignant gliomas, immunology