A Phase 1 Study of ALN-BCAT as Monotherapy and in Combination with Pembrolizumab inPatients With Advanced or Metastatic Hepatocellular Carcinoma

Contact:

NCT Number:

Protocol:

AAAV5831

Study Status:

Active/Enrolling

Population:

Adult

Phase:

I

The purpose of this study is to test the safety of an investigational drug called ALN-BCAT, and find out what effects, if any, ALN-BCAT has on people with your type of liver cancer. The effects being studied include: • The frequency and severity of side effects (to determine if the drug is safe) • Whether ALN-BCAT may make tumors smaller • How ALN-BCAT may affect the genes and proteins in your cancer cells • How your body processes ALN-BCAT

Are you Eligible? (Inclusion Criteria)

  • Age 18 years or older - Patient able to understand and willing and able to comply with requirements provided in consent form - Patients must have unresectable locally advanced or metastatic HCC

Specialty Area(s)

Liver Cancer

Principal Investigator

Trial Location(s)

CUIMC/Herbert Irving Pavilion
161 Fort Washington Avenue
New York, NY 10032