News

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Thousands of different genetic mutations have been implicated in cancer, but a new analysis, led by Andrea Califano, Dr, and Cory Abate-Shen, PhD, of almost 10,000 patients found that regardless of the cancer’s origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the master regulator proteins that control the cancer’s transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.
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A new study, led by members of the HICCC, has found that up to 20% of glioblastomas—an aggressive brain cancer—are fueled by overactive mitochondria and may be treatable with drugs currently in clinical trials.
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In December 2020, the United States FDA authorized two approved COVID-19 vaccines. HICCC Deputy Director Gary Schwartz, MD, addresses what patients with cancer should know about the new COVID-19 vaccine.
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CAR T-cell therapy is a promising type of treatment that re-engineers a patient’s white blood cells to recognize and kill tumor cells. For patients with certain types of lymphoma and leukemia who have exhausted all other options, including chemotherapy and bone marrow transplantation, CAR T-cell therapy has worked when nothing else has.
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Congratulations to Drs. Juan Arriaga and Jessica Hawley for winning the 2020 PCF Young Investigator Award in support of their work in prostate cancer research.
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A new study by researchers in medicine and in systems biology is investigating the airway epithelium, or lining, of the lungs, to investigate potential druggable targets for COVID-19.
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New research by Jacob Cogan, MD, a fellow in hematology/oncology, has revealed that breast cancer patients who receive mastectomy and reconstructive surgery may face the risk of developing persistent use of opioids and sedative-hypnotic drugs. The work was presented at the 2020 San Antonio Breast Cancer Symposium, a leading conference for experts in breast cancer research and care.
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December 1, 2020
Front Page

New Target to Treat Multiple Myeloma

Dr. Suzanne Lentzsch and her team have recently identified a promising new drug target in a subset of multiple myeloma cases, those with RAS mutations. The research was published in the journal Blood.
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Jane Hanley was devastated when she learned she had advanced lung cancer. Nearly five years later, Jane has a new outlook on life under the care and trust of her devoted oncology team at Columbia/NewYork-Presbyterian.
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