The weekly DNA Dynamics Webinar Series, Social DNAing, sponsored by the Cancer Genomics and Epigenomics Program of the Herbert Irving Comprehensive Cancer Center at Columbia University, aims to provide a virtual meeting room for the genomic instability community across the world.

The series began on June 18th, 2020. The talks begin at noon EST (US) every Thursday via Zoom. Recording of the most recent talk will be available for ~24 hours after the seminar with permission from the speaker.

Organized by

Shan Zha, MD, PhD

Jean Gautier, PhD


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Registration is free but required for attending the webinar. Register here
A confirmation email including an unsubscription option should reach you shortly upon successful email signup. A Zoom webinar link should follow the registration. If you did not receive the confirmation or the zoom link, please check the email address and try again. Please note webinar sign up is required to receive the Zoom link and can not be substituted by email signup.

For more information, please email

Upcoming Webinars

January 21, 2021 - RISING STARS

Constance Alabert, PhD, University of Dundee
"Disruption and restoration of euchromatin and heterochromatin in cycling cells"

Gheorghe Chistol, PhD, Stanford University
"Trainspotting with KEHRMIT: Single-Molecular Studies of Genome Maintenance"

Hee-Won Yang, PhD, Columbia University
"Regulation of the cell cycle by the DNA damage response pathway"

January 28, 2021

Patrick Sung, PhD, University of Texas, San Antonio
"Chromosome Damage Repair via tha BRCA Tumor Suppressor Axis"

Additional Upcoming Webinars


February 4, 2021

Simon Boulton, PhD, Francis Crick Institute

February 11, 2021

Houra Merrikh, PhD, Vanderbilt University
"DNAing in bacteria"

February 18, 2021

Shiv Grewal, PhD, NIH/NCI

February 25, 2021

Dana Branzei, PhD, IFOM and IGM-CNR
"Formulation and resolution of replication-associated recombination intermediates."

March 4, 2021

Abby Dernburg, PhD, University of California, Berkeley
"Patterning meiotic recombination"

March 11, 2021

Andrew Holland, PhD, Johns Hopkins University
"Centrosome homeostasis in development and disease"

March 18, 2021 - RISING STARS

Arvind Panday, PhD, Harvard Medical School
"Genetic Interaction between BRCA1 and FANCM in stalled fork repair"

James M Daley, PhD, University of Texas, San Antonio
"BRCA1-BARD1 functions in homologous recombination"

Corentin Claeys Bouuaert, PhD, UC Louvain
"Novel insights into the formation of meiotic DNA double-strand breaks"

March 25, 2021

Maria Jasin, PhD, MSKCC
"Life without the BRCA2 DBD"

April 1, 2021

Chris Lord, PhD, The Institute of Cancer Research
"Exploiting synthetic lethality to target cancer"

April 8, 2021

Vincenzo Constanzo, PhD, IFOM
"Understanding causes and consequences of DNA replication stress"

April 15, 2021

Anthony K. L. Leung, PhD, Johns Hopkins University

April 22, 2021

Andrew Jackson, PhD, The University of Edinburgh
"Human disorders of genome instability and replication"

April 29, 2021

Scott Keeney, PhD, MSKCC
"Mechanism and regulation of meiotic recombination initiation"

May 6, 2021

Eli Rothenberg, PhD, NYU

May 13, 2021

Titia de Lange, PhD, Rockefeller University

May 20, 2021 - Meet the Editors at 10 am

Angela Eggleston, PhD, Nature

Julia Sale, Nucleic Acids Research

Lara Szewczak, PhD, Cell

Brian Plosky, PhD, Molecular Cell

Jie Wang, PhD, Nature Cell Biology

Beth Moorefield, PhD, Nature Structural and Molecular Biology

Anne Mirabella, PhD, Nature Communication
May 20, 2021

Sharon Cantor, PhD, University of Massachusetts Medical School
"Focusing on the Gaps in Chemotherapy Response"

May 27, 2021

Karolin Luger, PhD, University of Colorado/HHMI
"Interesting stuff about Parp1 and its inhibitors"

Past Speakers

June 18, 2020
Lorraine Symington, PhD, Columbia University
"Role of the Mre11 complex in sensing and repairing DNA damage"

June 25, 2020
Lee Zou, PhD, Harvard Medical School, MGH Cancer Center
"The ATR signaling pathway: from basic research to targeted cancer therapy"

July 2, 2020
Roger Greenberg, PhD, University of Pennsylvania
"Chromatin accessibility: a new vulnerability in homologous recombination deficient cancers"

July 9, 2020
Sue Jinks-Robertson, PhD, Duke University
"Topoisomerase and genetic instability: lessons from yeast"

July 16, 2020
Ivan Ahel, PhD, University of Oxford
"ADP-ribosylation signalling in regulation of genome stability"

July 23, 2020 - Rising STARS
Brooks Crickard, PhD, Columbia University (Recommended by Eric Greene)
"Rad54 drives ATP-hydrolysis dependent DNA sequence alignment during homologous recombination"

Nikhil Bhagwat, PhD, University of California at Davis (Recommended by Neil Hunter)
"An essential role for SUMO in meiotic DSB formation revealed by global proteomics"

Yi Yin, PhD, University of California, Los Angeles (Recommended by the organizer)
"Development of a full-fledged mapping platform for mitotic crossover by single-cell multi-omics"

July 30, 2020
Taekjip Ha, PhD, Johns Hopkins University & HHMI
"Very fast CRISPR on demand"

August 6, 2020
Orlando D. Schärer, PhD, Ulsan National Institute of Science and Technology
"Replicative and TLS Polymerases in ICL Repair"

August 13,  2020
Neil Hunter, PhD, University of California at Davis
"MutS and MutL Make out in Meiosis"

August 20, 2020
Steven Henikoff, PhD, Fred Hutchinson Cancer Research Center & HHMI
"Genome-wide mapping of protein-DNA interaction dynamics"

August 27, 2020
David Cortez, PhD,
 Vanderbilt University
"New insights into genome maintenance during replication"

September 3, 2020
Anja Groth, PhD, University of Copenhagen
"Chromatic replication and genome maintenance"

September 10, 2020 - Rising STARS

Pierre Billon, PhD, Columbia University (Recommended by Alberto Ciccia)
"Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures"

Aakash Basu, PhD, Johns Hopkins University (Recommended by Taekjip Ha)
"Measuring DNA mechanics on the genome scale"

Kumar Somyajit, PhD, University of Copenhagen (Recommended by Jiri Lukas)
"Hypoxia disrupts replicating genomes

September 17, 2020
Daniel Durocher, PhD, The Lunenfeld-Tanenbaum Research Institute
"53BP1 recognition by RIF1: some answers and a new puzzle"

September 24, 2020
Wei Yang, PhD, National Institutes of Health (NIDDK)
"Programmed DSBs in initiation of V(D)J recombination"

October 1, 2020
Philippe Pasero, PhD, University of Montpellier
"Unintended Consequences of Replication Stress"

October 8, 2020
Kristijan Ramadan, PhD, University of Oxford
"DNA-protein crosslink proteolysis repair"

October 15, 2020
Karlene Cimprich, PhD, Stanford University
"The Causes and Consequences of Replication Stress"

October 22, 2020
Evi Soutoglou, PhD, University of Sussex
"How to maintain the integrity of the repetitive genome"

October 29, 2020
John Diffley, PhD, Francis Crick Institute
"Stalled Replication Forks and Checkpoints"

November 5, 2020
Keith Caldecott, PhD, University of Sussex
"DNA Strand Breakage and Human Genetic Disease"

November 12, 2020
Alberto Ciccia, PhD, Columbia University
"Interrogating the DNA damage response at higher resolution"

November 19, 2020 - Rising STARS

Eunhee Choi, PhD, Columbia University
"Spindle checkpoint regulators in insulin signaling"

Alejandro Álvarez-Quilón, PhD, The Lunenfeld-Tanenbaum Research Institute
"Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency"

Peter Ly, PhD, The University of Texas Southwestern Medical Center
"Mechanisms of Complex Genome Rearrangements from Cell Cycle Errors"

December 3, 2020
Ralph Scully, PhD, Harvard Medical School
"Mechanisms of stalled fork repair in mammalian cells"

December 10, 2020
Petr Cejka, PhD, University of Lugano
"Activation of the meiotic MHL1-MLH3 nuclease for crossover formation"

December 17, 2020
Agata Smogorzewska, PhD, Rockefeller University
"Molecular pathogenesis of disorders caused by DNA interstrand crosslink repair deficiency"

January 7, 2021
Bing Zhu, PhD, Institute of Biophysics, China
"Epigenetics: from inheritance to memory"

January 14, 2021

Tanya Paull, PhD, University of Texas, Austin
"Mechanisms of DNA double-strand break repair"