Researcher’s Profile

Alison Taylor, PhD

Body: 

Dr. Alison Taylor is a new faculty member at the Herbert Irving Comprehensive Cancer Center. Dr. Taylor received her PhD from Harvard University working in the laboratory of Dr. Leonard Zon, studying ribosomal protein mutations in blood development and disease. For her postdoctoral fellowship, she entered the field of cancer genomics in the laboratory of Dr. Matthew Meyerson, located at the Dana-Farber Cancer Institute and Broad Institute. Dr. Taylor is continuing to focus on understanding the role of aneuploidy in tumor development.

Email: at3488@cumc.columbia.edu

Research Statement: 

Dr. Taylor’s research is focused on incorrect chromosome number, termed aneuploidy. Aneuploidy was first observed in cancer in the early 1900s and is now known to occur in 90% of cancers. Recent advances in genomics and genome engineering approaches allow scientists to study specific aneuploidy alterations in the laboratory. The goal of Dr. Taylor’s research program is to use these methods to unravel the role of aneuploidy in tumorigenesis, both across cancer subtypes and in squamous cell carcinomas. In addition, she is interested in developing targeted therapies to aneuploid cancer cells.