Researcher’s Profile

Stephen G. Emerson, MD

Director, Herbert Irving Comprehensive Cancer Center
Research Statement: 

Dr. Emerson’s laboratory studies the genes shared by stem cell self-renewal programs and T cell memory developmental pathways.  He also serves as the Director of Columbia University’s Herbert Irving Comprehensive Cancer Center, in which role he recruits, integrates and supports basic, translational, and population research.

Publications: 

Emerson, S.G., Sieff, C.A., Wang, E.A., Wong, G.G., Clark, S.C., Nathan, D.G.:  Purification of fetal hematopoietic progenitors and demonstration of recombinant colony stimulating activity. J Clin Invest 76:1286-1290, 1985.

Taichman, R.S., Emerson, S.G.  Human osteoblasts support hematopoiesis through the production of granulocyte colony stimulating factor.  J Exp Med 179:1677-1682;1994. PMCID: PMC2191506

Taichman, R.S., Reilly, M.J., Emerson, S.G.  Human osteoblasts support human hematopoietic progenitor cells in long term in vitro bone marrow cultures.  Blood 87:518-524;1996.

Shlomchik, W., Couzens,M.S., Tang, C.B., McNiff, J., Robert, M.E., Liu, J., Shlomchik, M.J.,  Emerson, S.G. Prevention of Graft Versus Host Disease by Inactivation of Host Antigen-Presenting  Cells. Science 285:412-415, 1999.

Giannola, D., M. Jeganthesan, W. D. Shlomchik, D.N. Liebowitz, T. Kadesch, A. Dancis, S. G. Emerson. Hematopoietic expression of HOXB4 is regulated in normal and leukemic stem cells through transcriptional activation of the HOXB4 promoter by USF-1 and USF-2.  J. Exp. Med 192:1479-1490, 2000.