Cancer Regulatory Networks Major Themes

The program members come from nine basic-science departments and six clinical departments, and their research is focused under four major themes:

  • Cell-surface Receptors — proteins on the surfaces of cells that initiate a cellular response to external molecules
  • Intracellular Signaling Molecules — pathways or networks of interacting molecules that orchestrate the cellular response
  • Nuclear Oncoproteins and Tumor Suppressors — molecules acting within the nucleus to affect expression of genetic information
  • Angiogenic and Inflammatory Factors — molecules recruiting host cells to tumors to influence tumor growth