Physician’s Profile

Rebecca J. Leeman-Neill, MD, PhD

Department of Pathology & Cell Biology
Division of Anatomic Pathology
Introduction:
Board Certificates
Pathology - Hematology
Pathology - Anatomic
Honors & Awards:

2010 Robert E. Lee, MD Award for Excellence in Anatomic Pathology, University of Pittsburgh School of Medicine

2007 AACR-Women in Cancer Research Brigid G. Leventhal Scholar in Cancer Research Travel Award to AACR Frontiers in Cancer Prevention Research \

2007   American Society for Clinical Pathology Award for Academic Excellence and Achievement

2006   Scholar-in-Training Travel Award to AACR Frontiers in Cancer Prevention Research

Publications:

Gibson, SE, Leeman-Neill, RJ, Jain, S, Piao, W, Cieply, KM, Swerdlow, SH. “Proliferation centers of chronic lymphocytic leukemia/small lymphocytic lymphoma have enhanced expression of MYC protein, which does not result from rearrangement or gain of the MYC gene.” Br. J. Hematol 2016 Oct; 175(1):173-5.

Johnson, WT, Leeman-Neill, RJ, Patel, P, Ho, J, Grandinetti, L, Craig, FE, and Jedrych, J. “A Fatal Case of Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell lymphoma Initially Presenting with a CD4+ Phenotype: Progressive disease with Bexarotene and Romidepsin,” Am. J. Dermatopathol 2016 Nov; 38(11):832-837.

Bogdanova, TI, Zurnadzhy, LY, Nikiforov, YE, Leeman-Neill, RJ, Tronko, MD, Chanock, S, Mabuchi, K, Likhtarov, IA, Kovgan, LM, Drozdovitch, V, Little, MP, Hatch, M, Zablotska, LB, Shpak, VM, McConnell, RJ, Brenner, AV. “Histopathological features of papillary thyroid carcinomas detected during four screening examinations of a Ukrainian-American cohort.” Br. J. Cancer 2015 Dec; 113(11):1556-64.

Leeman-Neill, R.J., Kelly, L.M., Liu, P., Brenner, A.V., Little, M.P., Bogdanova, T.I., Evdokimova, V.N., Hatch, M., Zurnadzy, L.Y., Nikiforova, M.N., Yue, N.J., Zhang, M., Mabuchi, K., Tronko, M.D., Nikiforov, Y.E. “ETV6-NTRK3 is a common chromosomal rearrangement in radiation-associated thyroid cancer.” Cancer 2014 March; 120(6):799-807.

Leeman-Neill, R.J., Brenner, A.V., Little, M.P., Bogdanova, T.I., Maureen, H., Zurnadzy, L.Y., Mabuchi, K., Tronko, M.D., Nikiforov, Y.E. "RET/PTC and PAX8/PPARγ chromosomal rearrangements in post-Chernobyl thyroid cancer and their association with I-131 radiation dose and other characteristics." Cancer 2013 May; 119(10): 1792-9

Leeman-Neill, R.J., Seethala, R.R., Singh, S.V., Freilino, M.L., Bednash, J.S., Thomas, S.M., Panahandeh, M.C., Gooding, W.E., Joyce, S.C., Lingen, M.W., Neill, D.B., and Grandis, J.R. “Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma” Cancer Prev Res 2011 Feb; 4(2): 230-7

Wheeler, S.E., Suzuki, S., Thomas, S.M., Leeman-Neill, R.J., Chiosea, S.I., Kuan, C.T., Bigner, D.D., Gooding, W.E., Lai, S.Y., and Grandis, J.R. “Epidermal growth factor receptor variant III mediates head and neck cancer cell invasion via STAT3 activation” Oncogene 2010 Sep; 29(37): 5135-45

Leeman-Neill, R.J., Cai, Q., Joyce, S.C., Thomas, S.M., Bhola, N.E., Neill, D.B., Arbiser, J.L., and Grandis, J.R. “Honokiol inhibits EGFR signaling and enhances antitumor effects of EGFR inhibitors” Clin Cancer Res 2010 May; 16(9): 2571-9 4

Leeman-Neill, R.J., Wheeler, S.E., Singh, S.V., Thomas, S.M., Seethala, R.R., Neill, D.B., Panahandeh, M.C., Hahm, E., Joyce, S.C., Sen, M., Cai, Q., Li, C., Johnson, D.E., and Grandis, J.R. “Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3” Carcinogenesis 2009 Nov; 30(11): 1848-56.

Li, C., Sen, M., Leeman-Neill, R.J., Man, D.S., Grandis, J.R., and Johnson, D.E., “Bortezomib upregulates activated STAT3 and synergizes with inhibitors of STAT3 to promote head and neck squamous cell carcinoma cell death” Mol. Cancer Ther. 2009 Aug; 8(8): 2211-20

Lui, V.W., Boehm, A., Koppikar, P., Leeman, R.J., Johnson, D., Ogagan, M., Childs, E., Freilino, M., Grandis, J.R., “Antiproliferative mechanisms of a transcription factor decoy targeting STAT3: the role of STAT1,” Molec. Pharm. 2007 May; 71(5): 1435-43

Leeman, R.J., Lui, V.W., Grandis, J.R. “STAT3 as a therapeutic target in head and neck cancer.” Expert Opin Biol Ther. 2006 Mar; 6(3):231-41.