Researcher’s Profile

Glen S. Markowitz, MD

Vice Chair for Operations in Anatomic Pathology
Interim Vice Chair for Anatomic Pathology
Body: 
Research Statement: 

I am a renal pathologist with research interest in nephrotoxic patterns of renal injury, dysproteinemic forms of renal disease, and onconephropathology. Additional areas of interest include membranous nephropathy, morphologic variants of focal segmental glomerulosclerosis, lupus nephritis, ANCA-associated pauci-immune crescentic glomerulonephritis, and diabetic glomerulosclerosis.

Publications: 

1. Markowitz GS, Radhakrishnan J, Kambham N, Valeri AM, Hines WH, D’Agati VD. Lithium

nephrotoxicity: A progressive combined glomerular and tubulointerstitial nephropathy.

J Am Soc Nephrol. 11:1439-1448, 2000.

2. Markowitz GS, Appel GB, Fine PL, Fenves AZ, Jagannath S, Kuhn JA, Dratch AD, D’Agati

VD. Collapsing focal segmental glomerulosclerosis following treatment with high dose

pamidronate. J Am Soc Nephrol. 12(6):1164-1172, 2001.

3. Markowitz GS, Lin J, Valeri AM, Avila C, Nasr SH, D’Agati VD. Idiopathic nodular

glomerulosclerosis is a distinct clinico-pathologic entity linked to hypertension and

smoking. Human Pathol. 33:826-835, 2002.

4. Markowitz GS, Fine PL, Stack JI, Kunis CL, Radhakrishnan J, Palecki W, Park J, Nasr SH,

Hoh S, Siegel DS, D’Agati VD: Toxic acute tubular necrosis following treatment with

zoledronate (zometa). Kidney Int. 64:281-9, 2003.

5. Markowitz GS, Schwimmer J, Stokes MB, Nasr SH, Seigle RL, Valeri AM, D’Agati VD:

C1q nephropathy: A variant of focal segmental glomerulosclerosis. Kidney Int. 64:1232-1240, 2003.

6. Nasr SH, Markowitz GS, Stokes MB, Seshan SV, Valderrama E, Appel GB, Aucouturier P,

D’Agati VD: Proliferative glomerulonephritis with monoclonal IgG deposits: A distinct

entity mimicking immune-complex glomerulonephritis. Kidney Int. 65:85-96, 2004.

7. Stokes MB, Markowitz GS, Lin J, Valeri AM, D’Agati VD: Glomerular tip lesion: A distinct

entity within the minimal change disease /focal segmental glomerulosclerosis disease

spectrum. Kidney Int. 65:1690-1702, 2004.

8. Markowitz GS, Klein P, Anderson H, Stack JI, Alterman L, Price B, Nasr SH, Radhakrishnan

J, D’Agati VD: Renal failure and acute nephrocalcinosis following oral sodium phosphate

bowel cleansing. Human Pathol. 35:675-684, 2004.

9. Markowitz GS, Stokes MB, Radhakrishnan J, D’Agati VD: Acute phosphate nephropathy

following oral sodium phosphate bowel purgative: An under-recognized cause of chronic

renal failure. J Am Soc Nephrol. 16:3389-3396, 2005.

10. Stokes MB, Valeri AM, Markowitz GS, D’Agati VD: Cellular focal segmental

glomerulosclerosis: A distinct clinical-pathologic variant. Kidney Int. 70:1783-1792, 2006.

11. Nasr SH, D’Agati VD, Park HR, Sterman PL, Goyzueta JD, Dressler RM, Hazlett SM,

Pursell RN, Caputo C, Markowitz GS: Necrotizing and crescentic lupus nephritis with

anti-neutrophil cytoplasmic antibody seropositivity. Clin J Am Soc Nephrol.3:682-690, 2008.

12. Nasr SH, D’Agati VD, Said SM, Stokes MB, Largoza MV, Radhakrishnan J, Markowitz

GS: Oxalate nephropathy complicating Roux-en-Y gastric bypass: An underrecognized

cause of irreversible renal failure. Clin J Am Soc Nephrol. 3:1676-1683, 2008.

13. Nasr SH, Satoskar A, Markowitz, GS, Valeri AM, Appel GB, Stokes MB, Nadasdy T,

D’Agati VD: Proliferative glomerulonephritis with monoclonal IgG deposits: a report of

37 cases. J Am Soc Nephrol. 20:2055-64, 2009.

14. Herlitz LC, Markowitz GS, Farris AB, Schwimmer JA, Stokes MB, Kunis C, Colvin RB,

 D’Agati VD. Development of focal segmental glomerulosclerosis following anabolic

steroid use in bodybuilders. J Am Soc Nephrol. 21:163-172, 2010.

15. Markowitz GS, Nasr SH, Stokes MB, D’Agati VD. Treatment with interferon-alpha, -beta, or –gamma

is associated with collapsing focal segmental glomerulosclerosis. Clin J Am Soc Nephrol. 5:607-615, 2010.

16. Perazella MA, Markowitz GS. Drug-induced acute interstitial nephritis. Nat Rev Nephrol. 6:461-470, 2010.

17. Herlitz LC, Mohan S, Stokes MB, Radhakrishnan J, D’Agati VD, Markowitz GS. Tenofovir nephrotoxicity: acute 

tubular necrosis with distinctive clinical, pathologic, and mitochondrial abnormalities. Kidney Int. 78:1171-7, 2010.

18. Bomback AS, Appel GB, Radhakrishnan J, Shirazian S, Herlitz LC, Stokes B, D’Agati VD, Markowitz GS.

ANCA-associated glomerulonephritis in the very elderly. Kidney Int. 79:757-764, 2010.

19. Herlitz LC, D’Agati VD, Markowitz GS. Crystalline nephropathies. Arch Path Lab Med. 136:713-720, 2012.

20. Herlitz LC, Bomback AS, Stokes MB, Radhakrishnan J, D’Agati VD, Markowitz GS. IgA nephropathy with

minimal change disease. Clin J Am Soc Nephrol. 9:1033-9, 2014.

21. Markowitz GS, Bomback AS, Perazella MA. Drug-induced glomerular disease: Direct cellular injury.

Clin J Am Soc Nephrol. 10:1291-9, 2015.