Physician’s Profile

Michael D. Kluger, MD, MPH

Department of Surgery
Division of General Surgery
Medical Director, Milstein Hospital 6HS Surgical Oncology Unit
Introduction:

Dr. Michael Kluger is board-certified in general surgery and specialty trained in liver and pancreas surgery. He focuses on the operative management of pancreatic cancer, liver cancer, gallbladder disease and metastases to the liver and abdominal peritoneum. These complex diseases require treatment plans tailored to each patient's needs; therefore Dr. Kluger employs a multidisciplinary approach to determine the best available treatment options that maximize survival and quality of life. He is highly skilled in minimally invasive procedures, and uses laparoscopy whenever indicated.

Dr. Kluger graduated from the New York University School of Medicine, where he was elected to the Alpha Omega Alpha medical honor society and received awards for bioethics and community service. He completed his surgical residency at NewYork-Presbyterian Hospital/Columbia University Medical Center. There he was selected to be the Administrative Chief Resident and won the Gold Foundation Humanism and Excellence in Teaching Award. He received advanced training in liver transplantation and hepatobiliary surgery at Hospital Henri Mondor in France under the world-renowned surgeon Professor Daniel Cherqui. He is a Fellow of the American College of Surgeons, and a member of several prestigious professional organizations, including the Society of Surgical Oncology and the Society for Surgery of the Alimentary Tract.

Board Certificates
Surgery
Areas of Expertise:
  • Pancreatic Cancer
  • Liver Cancer
  • Hepatobiliary Surgery
  • Cancer Care
  • Pancreatic Surgery
  • Liver Surgery
  • Gallbladder Surgery
  • Duodenal cancer
  • Neuroendocrine Tumor
  • Gallbladder Cancer
  • Bile Duct Injury
  • Metastatic Cancer to Liver
  • Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
  • Cytoreduction
  • Mesothelioma of Peritoneum
  • Adrenal Cancer
Honors & Awards:

New York Presbyterian Hospital Physician of the Year, 2016

Society of Surgery of the Alimentary Tract, Hepatobiliary Sub-Committee, 2015

Super Doctors Rising Stars, 2015 & 2016

Teaching & Mentor Award, Department of Surgery, Columbia University, 2015

The Kenneth A. Forde Research Award, 2014

Excellence in Teaching Award, Weill Cornell Medical College, 2013

Presidential Poster of Distinction, American Association for the Study of Liver Diseases, 2011

European Society of Organ Transplantation Short Stay and Travel Grant, 2009

Philippe Foundation Award for Franco-American Scientific Collaboration, 2009

Humanism and Excellence in Teaching Award, Arnold P. Gold Foundation, 2007

Alpha Omega Alpha Medical Honor Society, 2004

Arthur Zitrin Award in Bioethics, 2004

New York Medical Society Community Service Award, 2004

Psi Chi National Psychology Honor Society, 1998

Publications:

Peer reviewed publications

- Rashid MF, Hecht EM, Steinman J, Kluger MD.  Irreversible Electroporation of Pancreatic Adenocarcinoma: A Primer for the Radiologist.  Abdominal Radiology. 2017 Oct 19. [Epub ahead of print] PMID: 29051982

- Heller D, Chiuzan C, Taub RN, Leinwand J, Greene A, Bates G, Chabot JA, Kluger MD.  Recurrence of optimally treated diffuse malignant peritoneal mesothelioma with cytoreduction and heated intraperitoneal chemotherapy.  Annals of Surgical Oncology.  [Epub ahead of print]. PMID: 29027138

- Steinman J, Zaheer A, Kluger MD, Remotti H, Hecht EM.  Rare Pancreatic Tumors. Abdominal Radiology. [Epub ahead of print]. PMID: 29022085.

- Kluger MD, Rashid MF, Rosario VL, Schrope BA, Steinman J, Hecht EM, Chabot JA.  Resection of locally advanced pancreatic cancer without regression of arterial encasement after modern-era neoadjuvant therapy.  Journal of Gastrointestinal Surgery.  [Epub ahead of print].  PMID: 28895032

- Ecker BL, McMillan MT, Bassi C, Beane JD, Beckman RM, Behrman SW, Dickson EJ, Callery MP, Christein JD, Drebin JA, Hollis RH, House MG, Jamieson NB, Javed AA, Kent TS, Kluger MD, Kowalsky SJ, Maggino L, Malleo G, Valero V, Velu LKP, Watkins AA, Wolfgang CL, Zureikat AH, Vollmer CM.  Risk Factors and Mitigation Strategies for Pancreatic Fistula after Distal Pancreatectomy: Analysis of 2,026 Resections from the International, Multi-institution Distal Pancreatectomy Study Group.  Annals of Surgery.  [Epub ahead of print].  PMID: 28857813

- Xu MM, Yin S, Siddiqui AA, Salem RR, Schrope B, Sethi A, Poneros JM, Gress FG, Genkinger JM, Do C, Brooks CA, Chabot JA, Kluger MD, Kowalski T, Loren DE, Aslanian H, Farrell JJ, Gonda TA. Comparison of the diagnostic accuracy of three current guidelines for the evaluation of asymptomatic pancreatic cystic neoplasms. Medicine (Baltimore). 2017 Sep;96(35):e7900. PMID: 28858107.

- Binhas M, Egbeola-Martial J, Kluger MD, Roudot-Thoraval F, Grimbert P.  Opioids and nonopioids for postoperative pain control in patients with chronic kidney disease.  J Opioid Manag. 2017;13(1):17-25.  PMID: 28345743

- Najjar M, Taylor A, Agrawal S, Fojo T, Merkler AE, Rosenblum MK, Lennihan L, Kluger MD.  Anti-Hu paraneoplastic brainstem encephalitis caused by a pancreatic neuroendocrine tumor presenting with central hypoventilation.  Journal of Clinical Neuroscience.  2017;40:72-73.  PMID: 28256369

- Hecht EM, Liu MZ, Prince MR, Jambawalikar S, Remotti HE, Weisberg SW, Garmon D, Lopez-Pintado S, Woo Y, Kluger MD, Chabot JA. Can diffusion-weighted imaging serve as a biomarker of fibrosis in pancreatic adenocarcinoma? J Magn Reson Imaging. 2017;46(2):393-402. PMID: 28152252

-  Yeh R, Steinman J, Luk L, Kluger MD, Hecht EM.  Imaging of pancreatic cancer: what the surgeon wants to know.  Clinical Imaging.  2016;7(42):203-217. PMID: 28110203.

-  Leinwand JC, Chabot JA, Kluger MD.  Preventing recurrence of diffuse malignant peritoneal mesothelioma.  Expert Review of Anticancer Therapy. 2016;16(9):989-95. PMID: 27486718

-  Parekh M, Kluger MD, Griesemer A, Bentley-Hibbert S.  Regenerative liver surgeries: the alphabet soup of emerging techniques.  Abdominal Radiology. 2016;41(1):162-73.  PMID: 26830622  

-  Kluger MD, Epelboym I, Schrope BA, et al. Single-Institution Experience with Irreversible Electroporation for T4 Pancreatic Cancer: First 50 Patients. Ann Surg Oncol. 2015 Dec 29.

-  Lee SY, Kingham TP, LaGratta MD, Jessurun J, Cherqui D, Jarnagin WR, Kluger MD. PET-avid hepatocellular adenomas: incidental findings associated with HNF1-α mutated lesions. Accepted for Publication 7/7/2015: HPB. PMID: 26472264.

-  Sugahara KN, Scodeller P, Braun GB, de Mendoza TH, Yamazaki CM, Kluger MD, et al. A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis. J Control Release. 2015;212:59-69. 

-  Kluger MD, Salceda JA, Laurent A et al. Liver resection for hepatocellular carcinoma in 313 Western patients: tumor biology and underlying liver rather than tumor size drive prognosis. J Hepatol. 2015;62(5):1131-40. 

-  Afaneh C, Gerszberg D, Slattery E, Seres DS, Chabot JA, Kluger MD. Pancreatic cancer surgery and nutrition management: a review of the current literature. Hepatobiliary Surg Nutr. 2015;4(1):59-71. 

-  Kluger MD, Halazun KJ, Barroso R, Fox AN, Olsen SK, Madoff DC, Siegel AB, Weintraub JL, Susman J, Brown RS, Cherqui D, Emond JC. Bland- versus chemo-embolization of hepatocellular carcinoma prior to transplantation. Liver Transplantation. 2014; 20(5): 536-543. PMID: 24493271.

-  Belin LJ, Neely R, Kluger MD. Techniques for safe organ recovery after endovascular aortic and bariatric surgery. Liver Transplantation. 2014; 20(5): 619-623 PMID: 24493164.

-  Kluger MD. Laparoscopic liver resection: basic skills for peripheral lesions (manuscript and video). Hepatobiliary Surgery and Nutrition. 2014; 3(1):44-46. PMID 24696837.

-  Afaneh C, Kluger MD. Laparoscopic liver resection: lessons at the end of the second decade. Semin Liver Dis. 2013;33(3):226-35. PMID: 23943103.

-  Emond JC, Kluger MD. International perspectives on advanced liver surgery. Semin Liver Dis. 2013;33(3):187-8. PMID: 23943099.

-  Kluger MD, Cherqui D. Laparoscopic resection of hepatocellular carcinoma. Recent Results Cancer Res. 2013;190:111-26. PMID: 22941017.

-  Kluger MD, Halazun KJ, Barroso R, Fox AN, Olsen SK, Madoff DC, Siegel AB, Weintraub JL, Susman J, Brown RS, Cherqui D, Emond JC. Bland- versus chemo-embolization of hepatocellular carcinoma prior to transplantation. Liver Transplantation. 2014; 20(5): 536-543. PMID: 24493271.

-  Lee SY, Mooney M, Inra M, Juluru K, Fox AN, Olsen SK, Brown RS, Emond JC, Cherqui D, Kluger MD. Exposure to ionizing radiation during liver transplantation evaluation, waitlisting, and post-operatively: a cause for concern. Hepatology. 2014; 59(2):496-504. PMID: 23904338

-  Kluger MD, Tayar C, Belli A, Salceda JA, Van Nhieu JT, Luciani A, Cherqui D. A foregut cystic neoplasm with diagnostic and therapeutic similarities to mucinous cystic neoplasms of the pancreas. JOP. 2013; 14(4):446-449. PMID: 23846945.

-  Eveno C, Karoui M, Gayat E, Luciani A, Auriault ML, Kluger MD, Baumgaertner I, Baranes L, Laurent A, Tayar C, Azoulay D, Cherqui D. Liver resection for colorectal liver metastases with peri-operative chemotherapy: oncological results of R1 resections. HPB. 2013; 15(5):359-364. PMID: 23458567.

-  Lee SY, Cherqui D, Kluger MD. Extended right hepatectomy in a liver with a non-bifurcating portal vein: the hanging maneuver protects the portal system in the presence of anomalies. Journal of Gastrointestinal Surgery. 2013; 17:1494-1499. PMID: 23404171.

-  Barrault C, Roudot-Thoraval F, Tran Van Nhieu J, Atanasiu C, Kluger MD, Medkour F, Douvin C, Mallat A, Zafrani ES, Cherqui D, Duvoux C. Non-invasive assessment of liver graft fibrosis by transient elastography after liver transplantation. Clin Res Hepatol Gastroenterol. 2013 Jan 10. [Epub ahead of print]. PMID: 23318116.

-  Santambrogio R, Kluger MD, Costa M, Belli A, Barabino M, Laurent A, Opocher E, Azoulay D, Cherqui D. Hepatic resection for hepatocellular carcinoma in patients with Child-Pugh’s A cirrhosis: is portal hypertension a contraindication? HPB, 2013; 15(1): 78-84. PMID: 23216782

-  Kluger MD, Vigano L, Barroso R, Cherqui D. The learning curve in laparoscopic major liver resection. J Hepatobiliary Pancreat Sci, 2013;20(2):131-6. PMID: 23064988

-  Kluger MD, Guarrera JV, Olsen SK et al. Safety of blood group A2-to-O liver transplantation: an analysis of the United Network of Organ Sharing database. Transplantation. 2012;94(5):526-31.

-  Goyer P, Karoui M, Vigano L, Kluger M, Luciani A, Laurent A, Azoulay D, Cherqui D. Single-center multidisciplinary management of patients with colorectal cancer and resectable synchronous liver metastases improves outcomes. Clin Res Hepatol Gastroenterol. 2013;37(1):47-55. PMID: 22521121

-  Duvoux C, Roudot-Thoraval F, Decaens T, Pessione F, Badran H, Wolf P, Francoz C, Compagnon P, Vanlemmens C, Dumortier J, Dharancy S, Gugenheim J, Bernard P, Adam R, Radenne S, Muscari F, Conti F, Hardwigsen J, Pageaux G, Chazoullières O, Salame E, Hilleret M, Lebray P, Abergel A, Debette-Gratien M, Kluger MD, Mallat A, Azoulay D, Cherqui D. Liver transplantation for hepatocellular carcinoma: a model including alpha-fetoprotein improves the performance of Milan criteria. Gastroenterology, 2012; 143(4):986-994. PMID: 22750200

-  Memeo R, Belli A, Kluger MD, Tayar, Laurent A, Cherqui D. Duct-to-duct biliary reconstruction during complex hepatectomy: A useful technique in selected cases. World Journal of Surgery, 2012, Jan; 36(1):129-35. PMID: 22037690

-  Kluger MD, Memeo R, Laurent A, Tayar C, Cherqui D. Survey of adult liver transplantation techniques (SALT): an international study of practices in full graft transplantation. HPB, 2011;13(10):692-8. PMID: 21929669

-  Hurtova M, Bachir D, Lee K, Calderaro J, Decaens, Kluger MD, Zafrani E, Cherqui D, Mallat A, Galacteros F, Duvoux C. Transplantation for liver failure in patients with sickle cell disease: challenging but feasible. Liver Transplantation, 2011; 17(4): 381-392. PMID: 21445921

-  Tayar C, Kluger MD, Laurent A, Cherqui D. Optimizing outflow in piggyback orthotopic liver transplantation: the 3-vein technique. Liver Transplantation, 2011; 17(1):88-92. PMID: 21254349

-  Vigano L, Kluger MD, Laurent A, Tayar C, Merle JC, Lauzet JY, Andreoletti M, Cherqui D. Liver resection in obese patients: results of a case-control study. HPB, 2011; 13(2):103-11. PMID: 21241427

-  Binhas M, Roudot-Thoraval F, Bonnet F, Lory C, Guerineau S, Jeanblanc G, Kluger MD, Marty J. Use of a validated reference tool to evaluate postoperative pain management through a quality-assurance program in a university hospital. Journal for Healthcare Quality, 2011; 33(1):7-13. PMID: 21199068

-  Kluger MD, Taub RN, Hesdorffer M, Chabot JA. Two-stage operative cytoreduction and intraperitoneal chemotherapy for diffuse malignant peritoneal mesothelioma: morbidity, mortality and survival in Phase I and II trials. European Journal of Surgical Oncology, 2010; 36(10):997-1003. PMID: 20674253

-  Weiss L, McCoy K, Kluger M, Finkelstein R. Access and use of health care: perceptions and experiences among people who use heroin and cocaine. Addiction Research and Theory, 2004; 12(2):155-165.

-  Kluger MD, Sofair AN, Heye CJ, Meek JI, Sodhi RK, Hadler JL. Retrospective validation of a surveillance system for unexplained illness and death: New Haven County, Connecticut. American Journal of