Researcher’s Profile

Angela J. Yoon, DDS

Director, Oral & Maxillofacial Pathology Division

Dr. Angela J. Yoon is the Chair of Oral and Maxillofacial Pathology Division at Columbia University College of Dental Medicine and has an interdisciplinary appointment in the Department of Pathology & Cell Biology at Columbia University College of Physicians and Surgeons. She holds a hospital appointment at Columbia University Medical Center and is the Director of the Oral Diagnostic Biopsy Service.


Research Statement: 

As an academic Oral & Maxillofacial Pathology clinician-scientist, Dr. Yoon is engaged in number of NIH and non-NIH funded clinical studies and trials, looking to improve oral cancer risk assessment and its management. In specific, Dr. Yoon's study focuses on translating laboratory science into new molecular risk assessment strategies, and improving therapies for oral neoplasms.

Phase IIa trial of Rosiglitazone (Avandia) for oral leukoplakia (Role: co-investigator, NCI-N01-CN35159, 2006-2008).
Inflammatory biomarkers in saliva: a case-control study to assess the oral inflammatory burden in patients with diagbetes mellitus (Role: co-investigator, 2008-2010).
Predictive value of microRNAs in the progression of oral leukoplakia (Role: co-investigator, NIDCR-R03-DE023820, 2014-2016).

Yoon et al. 'Activated checkpoint kinase 2 expression and risk for oral squamous cell carcinoma' Cancer Epidemiol Biomarkers Prev. 2007:1;2768-2772.

Yoon et al. 'Association between Gly1619ARG polymorphism of IGF2R domain 11 (RS629849) and advanced stage of oral cancer. Med Oncol. 2012;29:682-285.

Yoon et al. 'Topical application of green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) fro prevention of recurrent oral neoplastic lesions' JOFS 2012:4;43-45.

Yoon et al. 'Prognostic value of miR-375 and miR-214-3p in early stage oral squamous cell carcinoma' Am J Transl Res. 2014;6:580-592.