Physician’s Profile

Keith R. Brenner, MD

Department of Medicine
Division of Pulmonary, Allergy and Critical Care Medicine

Dr. Brenner graduated from the Johns Hopkins School of Medicine and performed postgraduate training at Columbia University Medical Center, completing residency in internal medicine and fellowship in pulmonary and critical care medicine.

Dr. Brenner’s focus is on providing excellent care to patients with pulmonary disease in the office and hospital setting. His clinical interests include interventional bronchoscopy, lung cancer screening, COPD, asthma, and interstitial lung disease. He participates in research studies of COPD treatment, bronchoscopic lung volume reduction for emphysema, and novel applications of extracorporeal membrane oxygenation (ECMO) as a treatment for respiratory failure.

Board Certificates
Pulmonary Disease
Internal Medicine
Critical Care Medicine
Areas of Expertise:
  • Lung Cancer
  • Cancer Care
Honors & Awards:
2005 Alpha Omega Alpha
2008 Arnold P. Gold Foundation, Humanism and Excellence in Teaching Award
2008-2009 Chief Resident, Internal Medicine Residency New York Presbyterian Hospital, Columbia University Medical Center
2011 American Thoracic Society Travel Award

Brenner K, Cunningham J, Bacchetta M, Brodie D. Catheter Associated Deep Vein Thrombosis And Level Of Anticoagulation In Adult Patients Requiring Extracorporeal Membrane Oxygenation For Respiratory Failure. American Thoracic Society. May 2012. Abstract 27987.


Brenner K, Baldwin MR, Agerstrand CL, Burkart KM, Bulman WA, Bacchetta MD, Brodie D. Improvements in dynamic pulmonary compliance with a very low tidal volume ventilation strategy and extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. Am J Respir Crit Care Med 183; 2011:A1648.


Baldwin MR, Bacchetta M, Brodie HD, Brenner K, Agerstrand C.L., Burkart K.M., Bulman W.A., Veno-venous extra corporeal membrane oxygenation with bi-caval dual lumen internal jugular catheter permits safe transport of adult patients with severe acute respiratory distress syndrome. Am J Respir Crit Care Med 183; 2011:A1649.


Agerstrand CA, Baldwin MR, Brodie HD Brenner K, Agerstrand C.L., Burkart K.M., Bulman W.A. Conservative blood transfusion strategies are effective for the management of adult patients with severe acute respiratory distress syndrome requiring extracorporeal membrane oxygenation. Am J Respir Crit Care Med 183; 2011:A1655.


Brenner K, Yip C, Cole S. A 25 year old pregnant woman with a large lung mass. Am J Respir Crit Care Med 181; 2010:A6873.


Keating CL, Wang S, Brenner K, Wang T, Powell C, Circulating Progenitor Cells in Non-Small Cell Lung Cancer Patients. American Thoracic Society. May 2008. Abstract 542.


Zimmer M, Ebert BL, Neil C, Brenner K, Papaioannou I, Melas A, Tolliday N, Lamb J, Pantopoulos K, Golub T, Iliopoulos O. Small-molecule inhibitors of HIF-2a translation links its 5’UTR ironresponsive element to oxygen sensing. Molecular Cell. 2008. 32: 838-48.


Abukhdeir AM, Vitolo MI, Argani P, De Marzo AM, Karakas B, Konishi H, Gustin JP, Lauring J, Garay JP, Pendleton C, Konishi Y, Blair BG, Brenner K, Garrett-Mayer E, Carraway H, Bachman KE, Park BH. Tamoxifen-stimulated growth of breast cancer due to p21 loss. Proceeding of the National Academy of Science. 2008. 105: 288-93.


Huang Y, Keen JC, Pledgie A, Marton LJ, Zhu T, Sukumar S, Park BH, Blair B, Brenner K, Casero RA Jr, Davidson NE. Polyamine analogues down-regulate estrogen receptor alpha expression in human breast cancer cells. Journal of Biological Chemistry. 2006. 281:19055-63.


Abukhdeir AM, Blair BG, Brenner K, Karakas B, Konishi H, Lim J, Sahasranaman V, Huang Y, Keen J, Davidson N, Vitolo MI, Bachman KE, Park BH. Physiologic estrogen receptor alpha signaling in non-tumorigenic human mammary epithelial cells. Breast Cancer Research and Treatment. 2005. 99:23-33.