Social DNAing

TBA

 

 

January 4th 2024

• Jean Cook    – University of North Carolina
  • "Replication origin licensing and proliferation control"

January 11th 2024

• Massimo Lopes – University of Zurich
  • "Replication fork plasticity in cancer and stem cells"

January 18th –  Rising STARs

• Zhiming Li – Columbia University
  • "Understanding parental histone deposition during DNA replication"
• Ryan Barnes – University of Kansas
  • "Oxidative and Replicative Stress at Telomeres"
• Chance Meer – Columbia University
  • "Transposon-encoded nucleases use guide RNAs to promote their selfish spread"

January 25th

• Julian Sale – University of Cambridge
  • Replication and genome evolution

February 1st

• Julien Duxin – University of Copenhagen
  • Mechanisms of DNA protein crosslink repair Or Mechanisms of translesion DNA synthesis

February 8th

• Yossi Shiloh – Tel Aviv University
  • Ataxia-Telangiectasia: A Vivid Demonstration of the Genome Stability-Ageing-Senescence Link

 

 

 

January 5, 2023

• Angelos Constantinou – IGH Montpellier
  • "Compartmentalization of the DNA damage response: mechanisms and functions"

January 12, 2023

• David Pellman – Harvard Medical School 
  • "Mechanisms driving rapid genome evolution"

January 19, 2023

•  Daniele Fachinetti  –  Institute Curie
  • "Mechanisms that control genome integrity at human centromeres"

January 26, 2023

• Don Cleveland – University of California San Diego
  • "Evolution of Genome Instability in Cancer"

February 2, 2023

• Jennifer Phillips-Cremins – University of Pennsylvania
  • "Heterochromatinization and folding of the repetitive genome"

February 9, 2023

•  Bruce Stillman – Cold Spring Harbor Laboratory
  • "Initiation of Chromosome Replication"

February 16, 2023:  Rising Stars

• Teresa Davoli – NYU
  • "Dissecting the consequences of chromosomal aneuploidy in cancer"
• Zhi Qi – Peking University
  • "Deciphering the dynamic mechanism of multiple Replication Protein A molecules binding to long single-stranded DNA"
• Courtney Clark-Hachtel – UNC Chapel Hill
  • "Mechanisms of extreme survival: Uncovering how tardigrades can tolerate extreme radiation"

February 23, 2023

• Samuel Bakhoum – MSKCC
  • "How chromosomal instability drives cancer progression"

March 2, 2023

• Yi Zhang – Harvard University
  • "eccDNAs: Mechanism of Biogenesis & Functions"

March 9, 2023

• Maria Spies – University of Iowa
  • "Replication protein A dynamics in cellular decision-making"

March 16, 2023

• Catherine Freudenreich – Tufts University
  • "Prevention of expansion and fragility of structure-forming repeats"

March 23, 2023

• Hongtao Yu – Westlake University
  • "Genome folding by cohesin"

March 30, 2023

• Carl Wu – Johns Hopkins University
  • "The Biogenesis and Maintenance of Chromatin Accessibility"

April 6, 2023

• Iestyn Whitehouse – MSKCC
  • "High-Resolution Views of DNA Replication"

April 13, 2023

• Zhongsheng You – Washington University
  • "A Ca2+-mediated signaling pathway for the protection of stressed replication forks"

April 20, 2023: Rising STARs

• Shrabasti Roychoudhury – Dana-Farber Cancer Institute    
  • "A high-throughput screening strategy identifies a novel regulator of replication stress response"
• Meng Wang – Cornell University
  • "Genotoxic aldehydes in cancer and aging"
• Vu Nguyen – Johns Hopkins University    
  • "Transcription regulation in living cells at single-molecule resolution"

April 27, 2023

• Thanos Halazonetis — University of Geneva
  • "DNA replication stress and cancer"

May 4, 2023

• Andreas Hochwagen – New York University
  • "Sources and function of rDNA instability"

May 11th:

• Helle Ulrich – IMB Mainz
  • "How to replicate damaged DNA"

May 18th

• Sherif El-Khamisy – University of Sheffield
  • "Chromosomal Break Repair at Gene Regulatory Elements"

May 25th

• Kyle Malcolm Miller – University of Texas at Austin
  • "Chromatin Mechanisms of Genome Integrity"

June 1st

• Andrew Blackford – Oxford University
  • "Novel insights into how the Bloom syndrome helicase maintains genome stability"

June 8th

• Matthias Altmeyer – University of Zurich
  • "Dynamics and functions of DNA repair compartments"

June 15th

• Danny Reinberg – New York University
  • "Polycomb, Inheritance and Disease"

June 22nd:  

• Laura J. Niedernhofer – University of Minnesota (POSTPONED)
  • "The role of DNA damage and cellular senescence in driving aging"

June 29th: Rising Stars

• Peggy Pei-Chi Wei – German Cancer Research Center (DKFZ)
  • "Genome Dynamics in the Developing Neuronal Cells"
• Thomas Clarke – Harvard Medical School
  • "Resection extension factor-1 (REF-1) links DNA double strand break repair to 22q11.2 distal deletion syndrome"
• Shintaro Yamada – Kyoto University
  • "A functional link between DNA double-strand break repair and the early transcriptional response to the sex hormone"

July 6th

• Lorenza Penengo – University of Zurich
  • "The interferon system regulates DNA replication and drug response via ISG15"

July 13th

• Ben Black – University of Pennsylvania
  • "Learning about the mitotic stability of natural chromosomes to make new ones"

July 20th:

• Kai Ge – National Institutes of Health (NIH)
  • "Enhancer regulation by H3K4me1 methyltransferases in differentiation, development and cancer"

July 27th

• John Petrini – Memorial Sloan Kettering Cancer Center
  • "Genetic analysis of double-strand break repair"

August 3rd

• Bik-Kwoon Tye – Hong Kong University of Science and Technology (HKUST)
  • "Forty-plus years of eukaryotic DNA replication"

August 10th

• Sven Rottenberg – University of Bern
  • "The study of mechanisms of anti-cancer therapy resistance using mouse models for BRCA1/2-mutated breast cancer"

August 17th

• Michele Pagano – New York University & Howard Hughes Medical Institute
  • "Cyclin D1 determines the activity of DNA mismatch repair in the G1 and S phases of the cell cycle"

August 24th: Rising Stars

• Weixing Zhao – University of Texas Health at San Antonio
  • "BRCA1-BARD1 E3 ligase licenses early and later stages of homology-directed repair"
• Glennis Logsdon – University of Washington
  • "The variation and evolution of human centromeres"
• Henriette Stoy – University Zurich
  • "Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids"

August 31st

• Anna Malkova – University of Iowa
  • "Break-Induced replication: genetics, kinetics and induced mutagenesis"

September 7th

• Martijn S. Luijsterburg – Leiden University Medical Center
  • "Molecular mechanisms in transcription-coupled DNA repair"

September 14th

• John C. Schimenti – Cornell University
  • "Impacts of genome instability during development"

September 21st

• Laura J. Niedernhofer – University of Minnesota
  • "The role of DNA damage and cellular senescence in driving aging"

September 28th

• Fabrizio d'Adda di Fagagna – IFOM
  • "RNA synthesis at double-strand breaks"

October 5th

• Lilian Kabeche – Yale University
  • "Redefining the function of ATR in genome stability"

October 12th: Rising STARs

• Priyanka Verma – Washington University
  • "Communication between base damage and replication-fork remodeling dictate responses to PARP inhibitor therapy in BRCA-mutant cancer"
• Gilad Evrony – New York University
  • "High-fidelity DNA sequencing of the single-strand origins of mutations"
• Wei Wu – The Chinese Academy of Sciences
  • "A Comprehensive Resource for Sequencing-based DNA Damage and Repair data"

October 19th

• Jeannine Gerhardt – Cornell University
  • "Causes and Consequences of Replication Stress"

October 26th

• Feilong Meng – The Chinese Academy of Sciences
  • "AIDed the Antibody Somatic Hypermutation with Flexible DNA"

November 2nd

• Jeff Gelles – Brandeis University
  • "Proteins flipping on DNA in replication and transcription"

November 9th

• Jiazhi Hu – Peking University
  • "Insights into DNA replication initiation and termination from the perspective of transcription and chromatin structure"

November 16th

• Susan Lees-Miller – University of Calgary
  • "The role of DNA-PKcs in NHEJ"

November 30th

• Sabrina Leigh Spencer – University of Colorado
  • "Escape from MAPK pathway inhibitors in cancer cells"

December 7th

• Ian D. Hickson – University of Copenhagen
  • "How are difficult-to-replicate regions of the human genome faithfully duplicated?"

December 14th

• Johnathan Whetstine – Fox Chase Cancer Center
  • "Epigenetics: A Gatekeeper to DNA Amplification and Rearrangements"

December 21st

• Guo-Min Li – UT Southwestern
  • "Diverse cellular functions of MLH1" (Cancelled – To Be Rescheduled)

January 6, 2022

• John Tainer, PhD, MD Anderson Cancer Center
  • "Non-B DNA and Nucleases at the Repair/Replication Interface and their Cancer Biology"

January 13, 2022

• Eric Greene, PhD, Columbia University
  • "Single-Molecule Studies of Homologous Recombination"

January 20, 2022

• Samuel H. Sternberg, PhD, Columbia University
  • "Targeted DNA Integration using CRISPR RNA-Guided Transposases"

January 27, 2022

• Geneviève Almouzni, PhD, Institute Curie
  • "A Parisian View on H3 Variants and Cell Fate"

February 3, 2022

• Stewart Shuman, PhD, MSKCC
  • "DNA Repair in Mycobacteria: A Helicase Perspective​"

Feb 10, 2022 (Rising Stars)

• Bob Reid, PhD, Columbia University
  • "Separation of Function Mutants Illuminate the Role of RAD5 in DNA Replication and Repair"
• Yael Nechemia-Arbely PhD, University of Pittsburgh
  • "Human Centromeres Drift Trough Cellular Proliferation​"
• Tom Deegan PhD, University of Edinburgh, MRC Human Genetics
  • "Mechanisms and Regulation of DNA Replication Termination​"

February 17, 2022

• Nima Mosammaparast, MD, PhD, Washington
  • "RNA Damage: The Canary in the Coal Mine?"

February 24, 2022

• Yuan He, PhD, Northwestern University
  • "Structural basis of DNA double-strand break repair by NHEJ"

March 3, 2022

• Joachim Lingner, PhD, Swiss Institute for Experimental Cancer Research (ISREC)
  • "TERRA R-loops and the challenges of telomere maintenance"

March 10, 2022

• Dirk Remus, PhD, MSKCC
  • "Mechanism of Sliding Clamp Loading in DNA Replication and DNA Damage Checkpoint Signaling"

March 17, 2022

• Niels Mailand, PhD, Novo Nordisk Foundation​
  • "SUMO Signaling in Genome Stability Maintenance​"

March 24, 2022

• John Maciejowski, PhD, MSKCC
  • "Innate Immunity to Genomic Instability​"

March 31, 2022

• Takehiko Kobayashi, PhD, The University of Tokyo
  • "It's an rDNA World"

April 7, 2022

• Dale Ramsden, PhD, University of North Carolina
  • "Nonhomologous and Theta-Mediated End Joining​"

April 14, 2022 (Rising Stars)

• Justin W. Leung, PhD, UAMS
  • "Chromatin-Based DNA Damage Response Pathway"
• Benjamin Stinson. PhD, Harvard Medical School
  • "How Non-Homologous End Joining Minimizes Errors​"
• Susanna Stroik, PhD, UNC
  • "Identification of a Key TMEJ Accessory Factor​​​"

April 21, 2022

• Daniel De Carvalho, PhD, University of Toronto
  • "Epigenetic Regulation of Endogenous Retroelements as an Emerging Vulnerability and Therapeutic Opportunity in Cancer Treatment and Interception​"

April 28, 2022

• Brian McStay, PhD, University of Galway
  • "Chromosomal context underpins nucleolar formation and rDNA genomic stability in human cells"

May 5, 2022

• Madalena Tarsounas – University of Oxford
  • "BRCA2 prevents DNA damage at early, but not late, replication origins"

May 12, 2022

• Maria Pia Longhese – University of Milano-Bicocca
  • "Functions and regulation of the MRX and Ku protein complexes at DNA double-strand breaks"

May 19, 2022

• Jessica Tyler – Weill Cornell Medicine
  • "Novel mechanisms regulating DNA end resection "

May 26, 2022

• Laura Landweber – Columbia University
  • "Oxytricha's scrambled genome"

May 5, 2022

• Madalena Tarsounas – University of Oxford
  • "BRCA2 prevents DNA damage at early, but not late, replication origins"

June 2, 2022

• Andrew Deans – St. Vincent's Institute
  • "Regulation and Roles of FANCI:FANCD2 Monoubiquitination"

June 9, 2022

• Daochun Kong – Peking University
  • "Cellular Regulation and Stability of DNA replication forks in eukaryotic cells"

June 16, 2022

• David Gilbert – San Diego Biomedical Research Institute
  • "Regulation of Replication Timing and Chromosome Architecture"

June 23, 2022

• Junjie Chen – MD Anderson Cancer Center
  • "Targeting DNA Damage Repair Pathways in Cancer Therapy"

June 30, 2022

• Robin Allshire – University of Edinburgh
  • "Epigenetic Regulation, Heterochromatin and Fungal Resistance"

July 7, 2022

• Bertrand Llorente – CNRS Marseille
  • "Homologous Recombination in Yeasts"

July 14, 2022 (Rising Stars)

• Robert Gnügge – Columbia University
  •  "The Sequence and Chromatin Context Influences Mre11-Rad50-Xrs2 Nicking at DNA Double-Strand Breaks"
• Sihan Wu – University of Texas Southwestern
  •  "Modern Biology of Extrachromosomal DNA in Human Cancer"
• Charles Ishak – Princess Margaret Cancer Centre/University of Toronto
  •  "Endogenous Retrotransposons and the Viral Mimicry Response During Early Tumorigenesis"

July 21, 2022

• Brittany S Adamson – Princeton University
  • "Mapping the Processes of DNA Repair During Genome Editing"

July 28, 2022

• Hilda Pickett – Children's Medical Research Institute
  • "Telomere Replication Stress: The Beginning and the End for ALT Cancers"

August 4, 2022

• Guoliang Xu – Chinese Academy of Sciences
  • "DNA cytosine modifications - the inheritance of parental influence beyond sequences"

August 11, 2022

• Qing Li – Peking University
  • "Replisome and histone chaperon orchestrate to guide histone partitioning during DNA replication"

August 18, 2022

• Scott Williams – National Institute of Environmental Health Sciences
  • "Molecular Mechanisms of DNA Repair Factors Impacted in Heritable Ataxia Syndromes"

August 25, 2022 (Rising Stars)

• Leng Siew Yeap – Shanghai Jiaotong University School of Medicine
  •  "The Genetic Pathways of Beneficial and Detrimental Insertions-Deletions"
• Feng Li – Dana-Farber Cancer Institute
  •  "The regulation of DNA repair pathway choice"
• Nausica Arnoult – Univ. of Colorado Boulder
  •  "Function of APE2 in DNA double-strand break repair"

September 1, 2022

• Rodney Rothstein – Columbia University
  • "Seeing is believing: break-induced mitotic recombination from 1936 to 2022"

September 8, 2022

• Alan D'Andrea – Dana-Farber Cancer Institute
  • "Overcoming PARP Inhibitor Resistance"

September 15, 2022

• Dorthe Helena Larsen – Danish Cancer Society Research Center
  • "rDNA instability and the nucleolar DNA damage response response"

September 22, 2022

• Dipanjan Chowdhury – Dana-Farber Cancer Institute
  • "Expanding the scope of DNA repair factors- novel roles and applications"

September 29, 2022

• Fumiko Esashi – University of Oxford
  • "Homologous Recombination: How, When, and Where Does It Act in Human Cells?"

October 6, 2022

•  Alice Pyne – University of Sheffield
  • "Ravelling the structure of supercoiled DNA with base-pair resolution"

October 13, 2022 (Rising Stars)

• Aurele Piazza  – Normale Supérieure de Lyon
  •  "Chromatin folding: role in recombinational break repair and implications for genome stability" 
•  Saini, Natalie – Medical University of South Carolina
  • "The mutation signature of acetaldehyde exposure in yeast and cancers"
• Matt Yousefzadeh – University of Minnesota
  • "Endogenous DNA damage as a driver of aging and dysfunction"

October 20, 2022

• Joseph Yeeles – MRC Laboratory of Molecular Biology
  • "The Eukaryotic Replisome: Structure and Mechanism"

October 27, 2022

•  Songtao Jia  – Columbia University
  • "Mechanism of heterochromatin assembly"

November 3, 2022

•  Michela Di Virgilio – Max-Delbrück-Center for Molecular Medicine
  • "Molecular Determinants of Antibody Gene Diversification"

November 10, 2022

• Zhiguo Zhang – Columbia University
  • "DNA replication coupled nucleosome assembly in the maintenance of genome and epigenome integrity"

November 17, 2022

• Thomas Helleday – Karolinska Institutet-Science Life Lab
  • "Targeting oxidative DNA repair"

December 1, 2022 (Rising Stars)

• Svasti Haricharan – Sanford Burnham Prebys
  • "DNA repair proteins in cancer: multi-tasking superheroes"
• Luke Yates – Imperial College London
  • "PIKK-ing apart the DNA Damage Response"
• Raquel Cuella-Martin – McGill University
  • "Precision genome editing screens to study gene (and protein) function"

December 8, 2022

• Roland Kanaar – Erasmus MC University Medical Center
  • "How a cancer-testis antigen interferes with BRCA2 function"

December 15, 2022

• Karl-Peter Hopfner – Ludwig-Maximilians-University
  • "Mechanism of Mre11-Rad50-Nbs1 in DNA double-strand break repair"

December 16, 2021

• Danesh Moazed, PhD, Harvard University
  • "How Epigenetic Memory is Propagated"

December 9, 2021

• Karim Labib, PhD, University of Dundee
  • "Destroying the Eukaryotic Replisome"

December 2, 2021

• Andrés Aguilera, PhD, CABIMER
  • "Prevention and Resolution of R Loop-mediated Transcription-Replication Conflicts"

November 18, 2021

• Sarah Lambert, PhD, Curie Institute
  • "The resolution of replication stress in space and time in fission yeast"

November 11, 2021

• Alessandro Vindigni, PhD, Washington University
  • "Linking replication fork dynamics to chemotherapy response"

November 4, 2021

• Jue Wang, PhD, University of Wisconsin, Madison
  • "Control of DNA Replication in Bacteria"

October 28, 2021

• Kara Bernstein, PhD, University of Pittsburgh
  • "A Precision Medicine Approach To Targeting Breast and Ovarian Tumors with RAD51C Mutations"

October 21, 2021

• Xin Chen, PhD, Johns Hopkins University & HHMI
  • "Breaking symmetry: asymmetric histone inheritance in multicellular organisms"

October 14, 2021

• Steve Bell, PhD, MIT
  • "Single-molecule Studies of Eukaryotic DNA Replication"

October 7, 2021

• Johannes Walter, PhD, Harvard Medical School
  • “The Mechanism of Vertebrate Replication Termination”

September 30, 2021

• Marco Foiani, PhD, IFOM
  • "Mechanisms coordinating the clash between replication and transcription"

September 23, 2021

• Xiaolan Zhao, PhD, MSKCC
  • "Understanding Smc5/6: from functions to structures"

September 16, 2021

• Agnel Sfeir, PhD, New York University
  • "A tale of two genomes: DNA repair in the mitochondria and the nucleus "

September 9, 2021

• Jim Haber, PhD, Brandeis University
  • "Mutations arising during repair of a broken chromosome"

September 2, 2021: Rising STARS

• Jaewon Min, PhD, Columbia University (Recommended by Jean Gautier)
  • "Mechanisms of chromosomal insertions" 
• Christian Zierhut, PhD, The Institute of Cancer Research (Recommended by Alberto Ciccia)
  • "Cancer cell fate decisions by innate immune self-DNA sensing"
• Agnieszka Lukaszewicz, PhD, MSKCC (Recommended by Maria Jasin)
  • “Mutagenic outcomes at recombination hotspots in mouse germlines”

August 26, 2021

• Jan Karlseder, PhD, Salk Institute
  • "A telomere driven nucleus to mitochondria pathway prevents cancer initiation"

August 19, 2021

• Irene Chiolo, PhD, USC
  • "DNA repair mechanisms in heterochromatin"

August 12, 2021

• Zhenkun Lou, PhD, Mayo Clinic
  • "Regulation of DNA End Resection"

August 5, 2021

• Joseph Loparo, PhD, Harvard Medical School
  • "Keeping it together: mechanistic studies of non-homologous end joining"

July 29, 2021

• Chao Lu, PhD, Columbia University
  • "Interplay between histone and DNA methylation in development and disease"

July 22, 2021: Rising STARs

• Alison Taylor, PhD, Columbia University (Recommended by Shan Zha/Jean Gautier)
  • "Functional and Computational Approaches to Studying Chromosome Arm Aneuploidy"
• Dan Semlow, PhD, California Institute of Technology (Recommended by Judith Campbell)
  • "Programmed formation of a DNA protein cross-link during DNA inter-strand cross-link repair" 
• Jennifer Urban, PhD, Johns Hopkins University (Recommended by Xin Chen)
  • "Studying DNA replication-dependent asymmetric histone incorporation in Drosophila germ cells using genomics"

July 15, 2021

• Geeta Narlikar, PhD, UCSF
  • "Heterochromatin through the lens of phase separation."

July 8, 2021

• Ross Chapman, PhD, Oxford University
  • “Regulation of DSB repair pathway choice by BRCA1, 53BP1 and friends”

July 1, 2021

• John Pascal, PhD, University of Montreal
  • "PARP enzymes in the cellular response to DNA damage."

June 24, 2021

• Andrew Jackson, PhD, The University of Edinburgh
  • "Human disorders of genome instability and replication" 

June 17, 2021

• Yonghao Yu, PhD, UT Southwestern
  • "Protein Poly-ADP-Ribosylation: Identification, Regulation and Translation." 

June 10, 202

• Upasana Roy PhD, Columbia University (Recommended by Eric Greene)
  • "Single-molecule insights into the role of Rad51 paralogs in homologous recombination" 
• Bo-Ruei Chen PhD, University of Alabama (Recommended by Barry Sleckman)
  • "Exploring novel functions of  the E3 ubiquitin ligase complex CTLH in DNA DSB end processing and repair"
• Francesca Mattiroli PhD, Hubrecht Institute (Recommended by Barry Sleckman)
  • "Mechanism of nucleosome assembly during DNA replication"

June 3, 2021

• Gaëlle Legube, PhD, University of Toulouse
  • "Chromatin and chromosome dynamics at DNA Double-Strand Breaks"  

May 27, 2021

• Karolin Luger, PhD, University of Colorado/HHMI
  • "Interesting stuff about Parp1 and its inhibitors"

May 20, 2021

• Sharon Cantor, University of Massachusetts Medical School
  • "Focusing on the Gaps in Chemotherapy Response"

May 20, 2021 Special Panel: "Meet the Editors On Genome Stability"

• Angela Eggleston, Nature
• Lara Szewczak, Cell
• Julian Sale, Nucleic Acids Research 
• Brian Plosky, Molecular Cell 
• Jie Wang, Nature Cell Biology
• Beth Moorefield, Nature Structural and Molecular Biology
• Anne Mirabella, Nature Communications

May 13, 2021

• Titia de Lange, PhD, Rockefeller University
  • "Telomeres and cancer: tumor suppression and genome instability."

May 6, 2021

• Eli Rothenberg, PhD, NYU
  • "Uncovering Key Processes in Replication Fork Remodeling and Repair via Single-Molecule Imaging."

April 29, 2021

• Scott Keeney, PhD, MSKCC
  • "Mechanism and regulation of meiotic recombination initiation"

April 22, 2021

• Andre Nussenzweig, PhD, NIH/NCI
  • "Maintenance of Genome Stability"

April 15, 2021

• Anthony K. L. Leung, PhD, Johns Hopkins University
  • "Tools to investigate poly(ADP-ribose) biology in DNA damage and beyond" 

April 8, 2021

• Vincenzo Constanzo, PhD, IFOM
  • "Understanding causes and consequences of DNA replication stress"

April 1, 2021

• Chris Lord, PhD, The Institute of Cancer Research
  • "Exploiting synthetic lethality to target cancer"

March 25, 2021

• Maria Jasin, PhD, MSKCC
  • "Life without the BRCA2 DBD"

March 18, 2021 - RISING STARS

• Arvind Panday, PhD, Harvard Medical School
  • "Genetic Interaction between BRCA1 and FANCM in stalled fork repair"
• James M Daley, PhD, University of Texas, San Antonio
  • "BRCA1-BARD1 functions in homologous recombination"
• Corentin Claeys Bouuaert, PhD, UC Louvain
  • "Novel insights into the formation of meiotic DNA double-strand breaks"

March 11, 2021

• Andrew Holland, PhD, Johns Hopkins University
  • "Centrosome homeostasis in development and disease"

March 4, 2021

• Abby Dernburg, PhD, University of California, Berkeley
  • "Patterning meiotic recombination"

February 25, 2021

• Dana Branzei, PhD, IFOM and IGM-CNR
  • "Formulation and resolution of replication-associated recombination intermediates."

February 18, 2021

• Shiv Grewal, PhD, NIH/NCI
  • "Dynamic regulation of the genome by RNA-based epigenetic mechanisms"

February 11, 2021

• Houra Merrikh, PhD, Vanderbilt University
  • "DNAing in bacteria"

February 4, 2021

• Simon Boulton, PhD, Francis Crick Institute
  • "Chromosome end protection"

January 28, 2021

• Patrick Sung, PhD, University of Texas, San Antonio
  • "Chromosome Damage Repair via the BRCA Tumor Suppressor Axis"

January 21, 2021 - RISING STARS

• Constance Alabert, PhD, University of Dundee
  • "Disruption and restoration of euchromatin and heterochromatin in cycling cells"
• Gheorghe Chistol, PhD, Stanford University
  • "Trainspotting with KEHRMIT: Single-Molecular Studies of Genome Maintenance"
• Hee-Won Yang, PhD, Columbia University
  • "Regulation of the cell cycle by the DNA damage response pathway"

January 14, 2021

• Tanya Paull, PhD, University of Texas, Austin
  • "Mechanisms of DNA double-strand break repair"

January 7, 2021

• Bing Zhu, PhD, Institute of Biophysics, China
  • "Epigenetics: from inheritance to memory"

December 17, 2020

• Agata Smogorzewska, PhD, Rockefeller University
  • "Molecular pathogenesis of disorders caused by DNA interstrand crosslink repair deficiency"

December 10, 2020

• Petr Cejka, PhD, University of Lugano
  • "Activation of the meiotic MHL1-MLH3 nuclease for crossover formation"

December 3, 2020

• Ralph Scully, PhD, Harvard Medical School
  • "Mechanisms of stalled fork repair in mammalian cells"

November 19, 2020 - Rising STARS

• Eunhee Choi, PhD, Columbia University
  • "Spindle checkpoint regulators in insulin signaling"
• Alejandro Álvarez-Quilón, PhD, The Lunenfeld-Tanenbaum Research Institute
  • "Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency"
• Peter Ly, PhD, The University of Texas Southwestern Medical Center
  • "Mechanisms of Complex Genome Rearrangements from Cell Cycle Errors"

November 12, 2020

• Alberto Ciccia, PhD, Columbia University
  • "Interrogating the DNA damage response at higher resolution"

November 5, 2020

• Keith Caldecott, PhD, University of Sussex
  • "DNA Strand Breakage and Human Genetic Disease"

October 29, 2020

• John Diffley, PhD, Francis Crick Institute
  • "Stalled Replication Forks and Checkpoints"

October 22, 2020

• Evi Soutoglou, PhD, University of Sussex
  • "How to maintain the integrity of the repetitive genome"

October 15, 2020

• Karlene Cimprich, PhD, Stanford University
  • "The Causes and Consequences of Replication Stress"

October 8, 2020

• Kristijan Ramadan, PhD, University of Oxford
  • "DNA-protein crosslink proteolysis repair"

October 1, 2020

• Philippe Pasero, PhD, University of Montpellier
  • "Unintended Consequences of Replication Stress"

September 24, 2020

• Wei Yang, PhD, National Institutes of Health (NIDDK)
  • "Programmed DSBs in initiation of V(D)J recombination"

September 17, 2020

• Daniel Durocher, PhD, The Lunenfeld-Tanenbaum Research Institute
  • "53BP1 recognition by RIF1: some answers and a new puzzle"

September 10, 2020 - Rising STARS

• Pierre Billon, PhD, Columbia University (Recommended by Alberto Ciccia)
  • "Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures"
• Aakash Basu, PhD, Johns Hopkins University (Recommended by Taekjip Ha)
  • "Measuring DNA mechanics on the genome-scale"
• Kumar Somyajit, PhD, University of Copenhagen (Recommended by Jiri Lukas)
  • "Hypoxia disrupts replicating genomes

September 3, 2020

• Anja Groth, PhD, University of Copenhagen
  • "Chromatic replication and genome maintenance"

August 27, 2020

• David Cortez, PhD, Vanderbilt University
  • "New insights into genome maintenance during replication"

August 20, 2020

• Steven Henikoff, PhD, Fred Hutchinson Cancer Research Center & HHMI
  • "Genome-wide mapping of protein-DNA interaction dynamics"

August 13, 2020

• Neil Hunter, PhD, University of California at Davis
  • "MutS and MutL Make out in Meiosis"

August 6, 2020

• Orlando D. Schärer, PhD, Ulsan National Institute of Science and Technology
  • "Replicative and TLS Polymerases in ICL Repair"

July 30, 2020

• Taekjip Ha, PhD, Johns Hopkins University & HHMI
  • "Very fast CRISPR on demand"

July 23, 2020 - Rising STARS

• Brooks Crickard, PhD, Columbia University (Recommended by Eric Greene)
  • "Rad54 drives ATP-hydrolysis dependent DNA sequence alignment during homologous recombination"
• Nikhil Bhagwat, PhD, University of California at Davis (Recommended by Neil Hunter)
  • "An essential role for SUMO in meiotic DSB formation revealed by global proteomics"
• Yi Yin, PhD, University of California, Los Angeles (Recommended by the organizer)
  • "Development of a full-fledged mapping platform for mitotic crossover by single-cell multi-omics"

July 16, 2020

• Ivan Ahel, PhD, University of Oxford
  • "ADP-ribosylation signalling in regulation of genome stability"

July 9, 2020

• Sue Jinks-Robertson, PhD, Duke University
  • "Topoisomerase and genetic instability: lessons from yeast"

July 2, 2020

• Roger Greenberg, PhD, University of Pennsylvania
  • "Chromatin accessibility: a new vulnerability in homologous recombination deficient cancers"

June 25, 2020

• Lee Zou, PhD, Harvard Medical School, MGH Cancer Center
  • "The ATR signaling pathway: from basic research to targeted cancer therapy"

June 18, 2020 (Inaugural Speaker)

• Lorraine Symington, PhD, Columbia University
  • "Role of the Mre11 complex in sensing and repairing DNA damage"